Fable Therapeutics
Using state-of-the-art machine learning models to create custom-build protein drugs
First Investment: 2021
To turn stem cells into the differentiated cells needed for cell therapy, companies typically augment cell cultures with cytokines, hormones, and growth factors. This process of “directed differentiation” is effective but slow. Syntax Bio invented a faster way: it uses transient plasmids to carry CRISPR-mediated instructions for activating and repressing key genes directly into cells, accelerating differentiation to the speed of human biology. By reducing the time required to generate high-value cell types, the company hopes to make cell therapy more affordable and accessible.
