Recursion Unveils LOWE Drug Discovery Software at the J.P. Morgan Healthcare Conference

SAN FRANCISCO, Jan. 08, 2024 (GLOBE NEWSWIRE) — Recursion (NASDAQ: RXRX), a leading clinical stage TechBio company decoding biology to indus­tri­alize drug discovery, today presented a demon­stra­tion of LOWE (Large Language Model-Orches­trated Workflow Engine), its new software designed to perform complex drug discovery tasks using a natural language interface. LOWE is powered by Recursion’s proprietary biological and chemical data and can orchestrate experiments using Recursion’s automated wet labo­ra­to­ries, unleashing the power of the Recursion Operating System in an easy-to-use tool.

“Recursion has spent the last 10 years building one of the world’s largest biological and chemical datasets, along with automated wet-lab and dry-lab tools that empower our scientists to move quickly to decode biology to discover and rapidly advance promising programs,” said Chris Gibson, Ph.D., Co-founder and CEO of Recursion. ​“For the first time, we’ve taught Large Language Models to use many of Recursion’s tools and data in the same way an expert scientist would, but much more simply and in a more scalable way. LOWE provides an exciting glimpse into what we believe the future of drug discovery will look like – a first step towards the development of autonomous ​‘AI scientists’ for therapeutic discovery.”

Chris Gibson unveiled LOWE during Recursion’s presen­ta­tion at the 42^nd Annual J.P. Morgan Healthcare Conference in San Francisco. On Wednesday, January 10, Recursion and NVIDIA will co-host an invite-only event featuring an exciting lineup of speakers and additional software demon­stra­tions of LOWE. Speakers at the event will include Jensen Huang, Founder and CEO of NVIDIA, Martin Chavez, Partner and Vice Chairman at Sixth Street Capital and Chairman of Recursion, Aviv Regev, Head and Executive Vice President of Research and Early Development at Genentech, Scott Gottlieb, Senior Fellow at the American Enterprise Institute, and Amy Abernethy, President of Product Development and Chief Medical Officer at Verily.

LOWE was developed at Valence Labs, Recursion’s AI research engine, following Recursion’s acquisition of Valence Discovery in May 2023. LOWE represents one of several initiatives Valence is pioneering to advance the future of AI-enabled scientific discovery, which includes the development of:

1. Foundation models that accurately represent or simulate the biological and chemical worlds of drug discovery
2. Inference engines and active learners to formulate hypotheses and learn from results
3. Orches­tra­tion and reasoning systems like LOWE that can design and execute experiments for hypothesis testing

To learn more about LOWE, visit recursion.com/lowe.

About Recursion

Recursion is a clinical stage TechBio company leading the space by decoding biology to indus­tri­alize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse tech­nolo­gies that contin­u­ously expands one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophis­ti­cated machine-learning algorithms to distill from its dataset a collection of trillions of searchable rela­tion­ships across biology and chemistry uncon­strained by human bias. By commanding massive exper­i­mental scale — up to millions of wet lab experiments weekly — and massive compu­ta­tional scale — owning and operating one of the most powerful super­com­puters in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.

Recursion is head­quar­tered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal and the San Francisco Bay Area. Learn more at www.Recursion.com, or connect on Twitter and LinkedIn.

About Valence Labs

Valence Labs, formerly Valence Discovery, is a company indus­tri­al­izing scientific discovery to radically improve lives. With roots at Mila and mentorship from Yoshua Bengio, the company is dedicated to advancing deep learning in drug discovery, delivering impactful research and trans­for­ma­tive technology, and embracing open-source and open-science knowledge sharing with the machine learning community.

Having bested industry giants in machine learning compe­ti­tions and after gaining a deeper under­standing of drug discovery intricacies, they teamed up with Recursion to combine Valence’s models with Recursion’s fit-for-purpose datasets to make better predictions and choose better experiments with a lower failure rate, at greater speed, and at a lesser cost. Combining the intel­lec­tual freedom of academia with the resources and stability of industry, Valence Labs takes a long-term view on technology development: acting boldly, leaning into risks, embracing failure, and ultimately trading incremental improve­ments for the break­through advances they hope will redefine the field. Learn more at www.ValenceLabs.com, or connect on Twitter and LinkedIn.

Forward-Looking Statements

This document contains information that includes or is based upon ​“forward-looking statements” within the meaning of the Securities Litigation Reform Act of 1995, including, without limitation, those regarding early and late stage discovery, preclinical, and clinical programs, including timelines for data readouts; licenses and collab­o­ra­tions, including option exercises by partners and additional part­ner­ships; prospective products and their potential future indications and market oppor­tu­ni­ties; Recursion OS and other tech­nolo­gies; business and financial plans and performance, including cash runway; and all other statements that are not historical facts. Forward-looking statements may or may not include identifying words such as ​“plan,” ​“will,” ​“expect,” ​“anticipate,” ​“intend,” ​“believe,” ​“potential,” ​“could,” ​“continue,” and similar terms. These statements are subject to known or unknown risks and uncer­tain­ties that could cause actual results to differ materially from those expressed or implied in such statements, including but not limited to: challenges inherent in phar­ma­ceu­tical research and development, including the timing and results of preclinical and clinical programs, where the risk of failure is high and failure can occur at any stage prior to or after regulatory approval due to lack of sufficient efficacy, safety consid­er­a­tions, or other factors; our ability to leverage and enhance our drug discovery platform; our ability to obtain financing for development activities and other corporate purposes; the success of our collab­o­ra­tion activities; our ability to obtain regulatory approval of, and ultimately commer­cialize, drug candidates; our ability to obtain, maintain, and enforce intel­lec­tual property protections; cyber­at­tacks or other disruptions to our technology systems; our ability to attract, motivate, and retain key employees and manage our growth; inflation and other macro­eco­nomic issues; and other risks and uncer­tain­ties such as those described under the heading ​“Risk Factors” in our filings with the U.S. Securities and Exchange Commission, including our most recent Quarterly Report on Form 10‑Q and our Annual Report on Form 10‑K. All forward-looking statements are based on management’s current estimates, projections, and assumptions, and Recursion undertakes no obligation to correct or update any such statements, whether as a result of new information, future devel­op­ments, or otherwise, except to the extent required by applicable law.